Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension. Coppi, A., Cabinian, M., Mirelman, D., and Sinnis, P. Antimalarial activity of allicin, a biologically active compound from garlic cloves. Pereira, F., Hatia, M., and Cardoso, J. View abstract. View abstract. De, B. K., Dutta, D., Pal, S. K., Gangopadhyay, S., Das, Baksi S., and Pani, A. Effect of samgyetang feeding on plasma lipids, glucose, glycosylated hemoglobin, and stress-induced gastric ulcers in mice. View abstract. Bruynzeel DP. View abstract. Garlic might increase how quickly the liver breaks down some medications. Am J Clin Nutr 1997;65:445-50. 2004;15(6):373-377. J Natl Med Assoc 1997;89:673-8. Garlic powder and plasma lipids and lipoproteins, a multicenter, randomized, placebo-controlled trial. View abstract. Ackermann RT, Mulrow CD, Ramirez G, et al. View abstract. You should not use garlic if you are allergic to it. 2001;131(3s):1061S-1066S. Pediatr Allergy Immunol. 1996;136(1):146-154. Witte JS, Longnecker MP, Bird CL, et al. View abstract. Onion and garlic intake and breast cancer, a case-control study in Puerto Rico. B. Garlic might increase the effectiveness of warfarin (Coumadin). Recent Pat Cardiovasc Drug Discov 2013;8(1):56-66. Kodali RT, Eslick GD. 2008;22(10):1372-1379. Int J Dermatol 2005;44:612-5. J Oral Pathol.Med 2002;31(3):142-146. View abstract. Effect of cooking on garlic (Allium sativum l.) Antiplatelet activity and thiosulfinates content. View abstract. J Indian Soc.Pedod.Prev.Dent. View abstract. View abstract. It also has anti-aging properties. Chinese Journal of Clinical Oncology 1998;25(5):338-340. Zeng T, Guo FF, Zhang CL, et al. Ter.Arkh. Am.J Clin Nutr. Carden SM, Good WV, Carden PA, Good RM. Cancer Res 10-15-2003;63(20):6825-6837. In vitro synergism of concentrated allium sativum extract and amphotericin B against cryptococcus neoformans. 2015;24(4):575-82. Garlic powder helps reduce your risk for heart disease. Helicobacter pylori infection, garlic intake and precancerous lesions in a Chinese population at low risk of gastric cancer. Lash, J. P., Cardoso, L. R., Mesler, P. M., Walczak, D. A., and Pollak, R. The effect of garlic on hypercholesterolemia in renal transplant patients. View abstract. View abstract. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study. A meta-analysis. A case of anaphylaxis after garlic ingestion: Is alliinase the only culprit allergen? A., Martirosyan, D. M., and Orekhov, A. N. The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease. View abstract. View abstract. View abstract. Curr.Med Res Opin. Planta Med 1989;55:114. Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats. Effects of garlic on blood fluidity and fibrinolytic activity: a randomised, placebo-controlled, double-blind study. Huang, J., Frohlich, J., and Ignaszewski, A. P. The impact of dietary changes and dietary supplements on lipid profile. Int J Epidemiol 1998;27:941-4. Dunstan, J. View abstract. A prospective cohort study on Allium vegetable consumption, garlic supplement use, and the risk of lung carcinoma in The Netherlands. Eur Phytojournal 2001;Symposium posters(1):1. Rockville, MD: Agency for Healthcare Research and Quality. Friedman, T., Shalom, A., and Westreich, M. Self-inflicted garlic burns: our experience and literature review. Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GARLIC. 2009;22:39-48. Ahmad, M. S., Pischetsrieder, M., and Ahmed, N. Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation. Prev.Med 1987;16(5):670-685. View abstract. Tu, H. K., Pan, K. F., Zhang, Y., Li, W. Q., Zhang, L., Ma, J. L., Li, J. Y., and You, W. C. Manganese superoxide dismutase polymorphism and risk of gastric lesions, and its effects on chemoprevention in a Chinese population. J Pharm.Pharmacol. 2020;99(1):e18575. View abstract. J Ethnopharmacol. Science 1997;278(5338):581. Stop using garlic and call your healthcare provider at once if you have: redness, swelling, or blistering (when applied to the skin); or. Indian J Exp Biol 1992;30(6):523-526. Thrush. Phytother.Res. View abstract. J Nutr 2006;136(3 Suppl):793S-795S. 4-30-2007;561(1-3):32-38. A., and Orekhov, A. N. [Study of the antioxidant drug "Karinat" in patients with chronic atrophic gastritis]. Garlic also provides a variety of anti-cancer properties. Effects of garlic consumption on plasma and erythrocyte antioxidant parameters in elderly subjects. Drug Chem.Toxicol. View abstract. van Ketel, W. G. and de Haan, P. Occupational eczema from garlic and onion. View abstract. Ip C, Lisk DJ. Some research suggests that eating more garlic does not prevent the development of lung cancer. Neurosurg 1990;26:880-2. Liu, C. T., Su, H. M., Lii, C. K., and Sheen, L. Y. View abstract. Contact Dermatitis 1992;27(5):333-334. A., and Pivovarova, E. M. Direct anti-atherosclerosis-related effects of garlic. Saravanan, G. and Prakash, J. Select one or more newsletters to continue. Handb.Exp.Pharmacol. Effect of garlic on lipid profile and psychopathologic parameters in people with mild to moderate hypercholesterolemia. Tunon, H. Garlic as a tick repellent. View abstract. Effects of garlic on lipid metabolism in rats fed cholesterol or lard. Singh, B. 2002;132(6):1165-1168. Contact Dermatitis 1976;2(1):28-42. View abstract. J.Dermatol. [Garlic and coronary heart disease. View abstract. Effect of garlic on total serum cholesterol. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. View abstract. Banerjee, S. K., Dinda, A. K., Manchanda, S. C., and Maulik, S. K. Chronic garlic administration protects rat heart against oxidative stress induced by ischemic reperfusion injury. Free Radic.Biol Med 10-1-2000;29(7):602-611. A typical dose is one 300 milligram (mg) dried garlic powder tablet two to three times a day, or 7.2 grams (g) of aged garlic extract per day. Do not give any herbal/health supplement to a child without medical advice. Contact dermatitis due to topical treatment with garlic in Hong Kong. Early research suggests that taking a liquid garlic extract daily for one month reduces prostate mass and urinary frequency. Toxicol.Appl.Pharmacol. View abstract. J Nutr. View abstract. Aged garlic extract may be safe for patients on warfarin therapy. View abstract. What’s more, the water soluble powder extract of garlic helps to stave off these side effects by limiting the amount of acid and its effect. Int J Cancer 10-15-1989;44(4):611-616. Contact Dermatitis 2006;55(3):193-194. Comparative study of lifestyles of residents in high and low risk areas for gastric cancer in Jiangsu Province, China; with special reference to allium vegetables. The dose of your warfarin (Coumadin) might need to be changed. Macan H, Uykimpang R, Alconcel M, et al. The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis. Wien.Med Wochenschr. Ernst E. Is garlic an effective treatment for Helicobacter pylori infection? 8-16-2002;2:16. Qureshi A, Abuirmeileh N, Din Z, and et al. Jabbari, A., Argani, H., Ghorbanihaghjo, A., and Mahdavi, R. Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in Renal Transplant Recipients. View abstract. Planta Med 2000;66:148-51. View abstract. Ashraf, R., Khan, R. A., and Ashraf, I. Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients. Arzneimittelforschung 1993;43:119-22. 2016;25(4):624-33. Prostaglandins Leukot Essent Fatty Acids 1999;60:43-7. Int Arch.Allergy Immunol. 2009;87(8):633-640. Applying a gel containing 1% ajoene, a chemical in garlic, seems to be effective for treating athlete's foot. J Atheroscler.Thromb. Taking garlic along with some medications used for HIV/AIDS might decrease the effectiveness of some medications used for HIV/AIDS. Pharm J 1991;246:722. Hansson LE, Nyren O, and Bergstrom R. Diet and risk of gastric cancer: a population-based case-control study in Sweden. Qureshi AA, Din ZZ, Abuirmeileh N, et al. 2010;27(10):787. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. View abstract. Rivlin, R. S. Historical perspective on the use of garlic. People seem to be more satisfied with garlic than the drug nystatin, but it is less effective. Vegetables, fruit, and colon cancer in the Iowa Women's Health Study. Mechanism of antioxidation, inhibiting carcinogenesis and modification of LDL of aged garlic extract. View abstract. Sabitha, P., Adhikari, P. M., Shenoy, S. M., Kamath, A., John, R., Prabhu, M. V., Mohammed, S., Baliga, S., and Padmaja, U. Efficacy of garlic paste in oral candidiasis. Tsai PB, Harnack LJ, Anderson KE, and et al. View abstract. Effect of dried garlic supplementation on blood lipids in mild and moderate hypercholesterolemic patients. Z Phytother 1984;5:938-942. Jpn.J Cancer Res 1999;90(6):614-621. J Nutr. Campos, R., Amato, Neto, V, Castanho, R. E., Moreira, A. Nagaraj, N. S., Anilakumar, K. R., and Singh, O. V. Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway. View abstract. Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GARLIC. View abstract. Sparnins, V. L., Barany, G., and Wattenberg, L. W. Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Takeuchi, S., Matsuzaki, Y., Ikenaga, S., Nishikawa, Y., Kimura, K., Nakano, H., and Sawamura, D. Garlic-induced irritant contact dermatitis mimicking nail psoriasis. The body breaks down medications used for HIV/AIDS to get rid of them. View abstract. A randomized trial of the effects of garlic oil upon coronary heart disease risk factors in trained male runners. View abstract. J.Burn Care Res. Carcinogenesis 1983;4(8):1063-1065. View abstract. Bordia, A. Clin Infect Dis 2002;34:234-8. Chin Med J (Engl.) Allium sativum (garlic) and cancer prevention. Orekhov, A. N., Tertov, V. V., Sobenin, I. Garlic ingestion by pregnant women alters the odor of amniotic fluid. Deutsche Apotheker Zeitung 1989;129(28 suppl 15):16-17. J Nutr 2001;131(3s):1080S-1084S. Gardner CD, Chatterjee LM, Carlson JJ. Br.J Clin Pract.Suppl 1990;69:20-23. An unusual garlic burn occurring on an unexpected area. Dirsch VM, Kiemer AK, Wagner H, Vollmar AM. J Spec Oper Med. Am.J Clin Nutr. View abstract. 1999;141(2):391-392. A case report. Gebhardt R, Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Subramanian P, Sundaresan S, and Manivasagam T. Influence of garlic extract on temporal characteristics of lipid peroxidation products and antioxidants in tumor-bearing rats. View abstract. Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate. Lau BH, Tadi PP, and Tosk JM. Gardner CD, Lawson LD, Block E, et al. View abstract. Clin.Nutr. Garlic as a possible risk for postoperative bleeding. Biochim Biophys Acta 1994;1213(1):57-62. Chiavarini M, Minelli L, Fabiani R. Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis. van der Walt, A., Lopata, A. L., Nieuwenhuizen, N. E., and Jeebhay, M. F. Work-related allergy and asthma in spice mill workers - The impact of processing dried spices on IgE reactivity patterns. View abstract. Ali, M. and Thomson, M. Consumption of a garlic clove a day could be beneficial in preventing thrombosis. Zhou, Y., Zhuang, W., Hu, W., Liu, G. J., Wu, T. X., and Wu, X. T. Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis. Cochrane.Database.Syst.Rev. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. Sahebkar A, Serban C, Ursoniu S, Banach M. Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials. The effects of garlic preparation against human tumour cell proliferation. Bleumink, E., Doeglas, H. M., Klokke, A. H., and Nater, J. P. Allergic contact dermatitis to garlic. Today, claims for the health benefits of garlic include lower blood pressure and cholesterol, an anti-inflammatory effect, a reduced risk of cancer, and a stronger immune system. View abstract. Mukherjee, M., Das, A. S., Das, D., Mukherjee, S., Mitra, S., and Mitra, C. Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol. Stabler, S. N., Tejani, A. M., Huynh, F., and Fowkes, C. Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients. Pinto, J. T., Qiao, C., Xing, J., Rivlin, R. S., Protomastro, M. L., Weissler, M. L., Tao, Y., Thaler, H., and Heston, W. D. Effects of garlic thioallyl derivatives on growth, glutathione concentration, and polyamine formation of human prostate carcinoma cells in culture. A meta-analysis of the effect of garlic on blood pressure. Contact Dermatitis 1991;24:193-6. Hiroshima J Med Sci. Pharmacotherapy 1993;13:406-7. View abstract. Ugeskr.Laeger 7-21-2003;165(30):2962-2963. View abstract. You may report side effects to FDA at 1-800-FDA-1088. Fedder, S. L. Spinal epidural hematoma and garlic ingestion. View abstract. View abstract. Early research suggests that administering garlic intravenously (by IV) for 10 days reduces chest pain compared to intravenous nitroglycerin. Calvet X, Carod C, Gene E. Re: Peppers at treatment for Helicobacter pylori infection. AIDS 2013;27:1361-2. Phytother.Res 2000;14:200-2. Health Canada. The impact of garlic on lipid parameters: a systematic review and meta-analysis. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Burnham BE. Arzneimittelforschung 1986;36:766-8. A pilot study to determine the effectiveness of garlic oil capsules in the treatment of dyspeptic patients with Helicobacter pylori. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others. View abstract. The antiatherosclerotic effect of Allium sativum. Phytother Res 2000;14(3):215-217. Zhang XH, Lowe D, Giles P, et al. Staba EJ, Lash L, Staba JE. 2020:postgradmedj-2019-137267. View abstract. J Nat Toxins. Salem, S., Salahi, M., Mohseni, M., Ahmadi, H., Mehrsai, A., Jahani, Y., and Pourmand, G. Major dietary factors and prostate cancer risk: a prospective multicenter case-control study. October 2000. Reduction in elevated blood lipids in hospitalised patients by a standardised garlic preparation. View abstract. Ranstam J. Garlic as a tick repellent. Contact Dermatitis 2000;42:108-9. Br J Pharmacol 2008;154:1691-700. View abstract. Phytother.Res. Br J Cancer 1997;76:678-87. Cystic fibrosis. View abstract. But the quality of this research is questionable. The blood pressure lowering and lipid lowering effect of a garlic preparation in combination with a diuretic. Bakri, I. M. and Douglas, C. W. Inhibitory effect of garlic extract on oral bacteria. Anticancer Drugs 1998;9(3):291-294. View abstract. Risk factors for multiple myeloma: a hospital-based case-control study in Northwest China. Taking garlic along with cyclosporine (Neoral, Sandimmune) might decrease the effectiveness of cyclosporine (Neoral, Sandimmune). Blood Coagul.Fibrinolysis 2001;12(1):67-74. Mulrow C, Lawrence V, Ackerman R, et al. Zhang, W. J., Shi, Z. X., Wang, B. Zhang S, Liu M, Wang Y, et al. Lipids Health Dis. When used as a medicinal product, garlic may produce both desired and … Morris J, Burke V, Mori TA, et al. What are the side effects of allicin? Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. View abstract. Garlic Fights Fungal Infections. Yuncu, M., Eralp, A., and Celik, A. Public Health Nutr. Ankri S, Mirelman D. Antimicrobial properties of allicin from garlic. 2018 Mar 23. 10-3-2003;73(20):2543-2556. Allicin is an organosulfur compound that is … A., Nedosugova, L. V., Filatova, L. V., Balabolkin, M. I., Gorchakova, T. V., and Orekhov, A. N. Metabolic effects of time-released garlic powder tablets in type 2 diabetes mellitus: the results of double-blinded placebo-controlled study. J Nutrit 1982;112(2):241-248. The body breaks down the estrogen in birth control pills to get rid of it. J Pharm Pharmacol 1997;49:908-11. Petry, J. J. Garlic and postoperative bleeding. Gallwitz, H., Bonse, S., Martinez-Cruz, A., Schlichting, I., Schumacher, K., and Krauth-Siegel, R. L. Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: crystallographic, kinetic, and spectroscopic studies. Do not use different forms (cloves, tablets, oil, etc) of garlic at the same time without medical advice. B., Vinjamury, S. P., Der-Martirosian, C., Kubik, E., Mishra, L. C., Shepard, N. P., Singh, V. J., Meier, M., and Madhu, S. G. Ayurvedic and collateral herbal treatments for hyperlipidemia: a systematic review of randomized controlled trials and quasi-experimental designs. View abstract. Phytother.Res. Santos OSDA and Grunwald J. Br J Dermatol. Belman, S. Onion and garlic oils inhibit tumor promotion. Emerg.Med.J. Avoid taking fish oil or vitamin E while you are taking garlic. Effect of milk on the deodorization of malodorous breath after garlic ingestion. 1997;25(1):99S. Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. J Nutr. View abstract. Ann Intern Med 1993;119:599-605. Call your doctor if the condition you are treating with garlic does not improve, or if it gets worse while using this product. It is unclear if eating more garlic can reduce the risk for cancer of the esophagus. 1991;29(4):151-155. Isoniazid (Nydrazid, INH) interacts with GARLIC. View abstract. Kumar, M. and Berwal, J. S. Sensitivity of food pathogens to garlic (Allium sativum). Int J Immunopharmacol. Sangouni AA, Mohammad Hosseini Azar MR, Alizadeh M. Effect of garlic powder supplementation on hepatic steatosis, liver enzymes and lipid profile in patients with non-alcoholic fatty liver disease: a double-blind randomised controlled clinical trial. Phytother.Res. View abstract. 2012;92:1892-1902. View abstract. Ann Allergy Asthma Immunol 2013;111(1):64-5. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Zhang S, Gu Y, Wang L, et al. Hughes BG, Murray BK, North JA, and et al. View abstract. Randomized comparative study with terbinafine. Sandhu, D. K., Warraich, M. K., and Singh, S. Sensitivity of yeasts isolated from cases of vaginitis to aqueous extracts of garlic. J Nutr. J Med Food 2009;12(4):776-781. Brosche, T., Platt, D., and Dorner, H. The effect of a garlic preparation on the composition of plasma lipoproteins and erythrocyte membranes in geriatric subjects. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Wongmekiat, O. and Thamprasert, K. Investigating the protective effects of aged garlic extract on cyclosporin-induced nephrotoxicity in rats. View abstract. View abstract. [Postprandial lipemia under treatment with Allium sativum. Orekhov AN, Pivovarova EM, and Tertov VV. Kiesewetter H, Jung F, Jung EM, et al. J Nutr Sci Vitaminol (Tokyo) 1999;45:785-90. Breast cancer. View abstract. Ledezma E, Marcano K, Jorquera A. Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine. View abstract. Therapiewoche 1988;38:3885-3890. View abstract. Pedraza-Chaverri J, Tapia E, Medina-Campos ON, et al. The antiatherosclerotic effect of Allium sativum. Ambati, S., Yang, J. Y., Rayalam, S., Park, H. J., Della-Fera, M. A., and Baile, C. A. Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis. J Ethnopharmacol. J Nutr 2000;130:2662-5. View abstract. 1995;20(1):14-18. 2009;8(1):2-10. Arch Intern Med 1999;159:2484-5. Melvin KR. The use of garlic as a flavoring agent in foods is considered safe during pregnancy. View abstract. If you're currently using blood-thinni… Lancet 4-27-1996;347(9009):1195. Neil HA, Silagy CA, Lancaster T, et al. Arztezeitschr Naturheilverf 1996;37:126-129. Steiner M, Li W. 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